Brian joined Triplet Therapeutics, Inc. in 2018 and serves as Senior Vice President, Research. Brian has held various leadership roles in bioinformatics and biostatistics, including most recently leading the Bioinformatics group at Translate Bio. He led the development of siRNA efficacy prediction in Bioinformatics and founded the Biometrics department at Alnylam Pharmaceuticals. Prior to moving to industry, Brian was a Biology professor with a research focus on Drosophila models of triplet expansion.